Carbon 60 Interview and Research

Tom Martin, Founder and CEO of C60OliveOil.com, joins Sarah Westall of Business Game Changers to discuss the amazing benefits of C60. Hear why the entire industry sold out of the product after her interview with Clif High!

Tom Martin, Founder and CEO of C60OliveOil.com, joins Sarah Westall of Business Game Changers to discuss the amazing benefits of C60. Hear why the entire industry sold out of the product after her interview with Clif High! (Here is the original interview - https://youtu.be/5xLrYL3rpIo)

You will learn that C60 has the potential to extend life. Hear about the amazing results and studies going on all over the world.

Wikipedia: A fullerene is a molecule of carbon in the form of a hollow sphere, ellipsoid, tube, and many other shapes. Spherical fullerenes, also referred to as Buckminsterfullerenes or buckyballs, resemble the balls used in association football. Cylindrical fullerenes are also called carbon nanotubes (buckytubes). Fullerenes are similar in structure to graphite, which is composed of stacked graphene sheets of linked hexagonal rings. Unless they are cylindrical, they must also contain pentagonal (or sometimes heptagonal) rings.
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C60 is a powerful antioxidant

This point is long known and confirmed in a number of studies.  From (2007) Medicinal applications of fullerenes:

“Results published in 1999 have shown that fullerenes have a potential as biological antioxidants. The antioxidant property is based on the fact that fullerenes possess large amount of conjugated double bonds and low lying lowest unoccupied molecular orbital (LUMO) which can easily take up an electron, making an attack of radical species highly possible. It has been reported that up to 34 methyl radicals have been added onto a single C60 molecule. This quenching process appears to be catalytic. In other words the fullerene can react with many superoxides without being consumed. Due to this feature fullerenes are considered to be the world’s most efficient radical scavenger and are described as radical sponges (Krusic et al 1991). The major advantage of using fullerenes as medical antioxidant is their ability to localize within the cell to mitochondria and other cell compartment sites, where in diseased states, the production of free radicals takes place. — Experiments on rats done by Najla Gharbi and coworkers proved this remarkable trait. They showed that aqueous C60 suspensions prepared without using any polar organic solvent, not only have no acute or sub acute toxicity in rodents, but also protect their livers against free-radical damage (Gharbi et al 2005).”

Fullerene C60 is neuroprotective

The 2001 publication Fullerene-based antioxidants and neurodegenerative disorders reports:

“Water-soluble derivatives of buckminsterfullerene (C60) derivatives are a unique class of compounds with potent antioxidant properties.  Studies on one class of these compounds, the malonic acid C60 derivatives (carboxyfullerenes), indicated that they are capable of eliminating both superoxide anion and H2O2, and were effective inhibitors of lipid peroxidation, as well. Carboxyfullerenes demonstrated robust neuroprotection against excitotoxic, apoptotic and metabolic insults in cortical cell cultures. They were also capable of rescuing mesence-phalic dopaminergic neurons from both MPP1 and 6-hydroxydopamine-induced degeneration. Although there is limited in vivo data on these compounds to date, we have previously reported that systemic administration of the C3 carboxyfullerene isomer delayed motor deterioration and death in a mouse model of familial amyotrophic lateral sclerosis (FALS). Ongoing studies in other animal models of CNS disease states suggest that these novel antioxidants are potential neuroprotective agents for other neurodegenerative disorders, including Parkinson’s disease.”

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The original study that inspired Tom's interest in Carbon 60 Olive Oil

Tarek Baati, Fanchon Bourasset, Najla Gharbi, Leila Njim, Manef Abderrabba, Abdelhamid Kerkeni, Henri Szwarc, Fathi Moussa, The prolongation of the lifespan of rats by repeated oral administration of [60]fullerene, Biomaterials, Volume 33, Issue 19, June 2012, Pages 4936-4946, ISSN 0142-9612, 10.1016/j.biomaterials.2012.03.036. (http://www.sciencedirect.com/science/article/pii/S0142961212003237)

Abstract: Countless studies showed that [60]fullerene (C60) and derivatives could have many potential biomedical applications. However, while several independent research groups showed that C60 has no acute or sub-acute toxicity in various experimental models, more than 25 years after its discovery the in vivo fate and the chronic effects of this fullerene remain unknown. If the potential of C60 and derivatives in the biomedical field have to be fulfilled these issues must be addressed. Here we show that oral administration of C60 dissolved in olive oil (0.8 mg/ml) at reiterated doses (1.7 mg/kg of body weight) to rats not only does not entail chronic toxicity but it almost doubles their lifespan. The effects of C60-olive oil solutions in an experimental model of CCl4 intoxication in rat strongly suggest that the effect on lifespan is mainly due to the attenuation of age-associated increases in oxidative stress. Pharmacokinetic studies show that dissolved C60 is absorbed by the gastro-intestinal tract and eliminated in a few tens of hours. These results of importance in the fields of medicine and toxicology should open the way for the many possible -and waited for- biomedical applications of C60 including cancer therapy, neurodegenerative disorders, and ageing. Keywords: Fullerenes; Toxicity; Pharmacokinetics; Ageing; Oxidative stress

The authors of the above paper have issued several corrections, most notably a correction to the survival chart, figure 3.
Here are the corrected data: http://www.sciencedirect.com/science/article/pii/S0142961212005522

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